Da Best in Da West is a comedy Western. Dolphy plays the role of Chango, a good for nothing vagabond who becomes sheriff because no one would accept the jo. Later he proves to be a real hero. Divina Valencia who stars opposite Dolphy for the first time plays the role of Calamity Jane, a showgirl daughter of the former sheriff who ha been killed. Jane worhips Chango and falls in love with him thinking that he is a real hero. Panchito is Ckint Eastwood, sidekick of Chango, a chicken thief who becomes deputy when Chango becomes sheriff. Rod Navarro is Da Kwelyo, the mastermind owner of saloon who wants to control the town.